Levels of small extracellular vesicles in patients treated with hyperbaric oxygenation
نویسندگان
چکیده
Introduction Hyperbaric oxygen (HBO2) therapy involves the inhalation of pure in a pressure chamber under increased ambient pressure. Recent research indicates that circulating small extracellular vesicles (sEVs) play important roles human physiology and pathology. Therefore, objective this pilot study was to monitor impact HBO2 on levels sEVs serum patients with necrotizing soft-tissue infections (NSTI), aseptic bone necrosis (ABN) or idiopathic sudden sensory neural hearing loss (ISSNHL). Material methods Serum-derived were isolated quantified 80 before after applied for NSTI, ISSNHL ABN as well normal controls who received neither nor steroids. Results We observed significant increase (p < 0.05), significantly elevated compared NSTI 0.05) 0.01). Conclusions The may be evidence both intended reduction inflammation result steroid inhibitory effect oxidative stress induced by therapy. Thus, released during might an biological role mediating response promising approach gain further insights into therapeutic efficacy
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Hyperbaric Oxygenation permits a controlled increase of the partial oxygen pressure in the blood. This technique can be used in cases of tinnitus and sudden deafness when the development in the inner ear and the brain lead to a lack of oxygen and so to a limited energy provision. The results to date allow the recommendation to apply an oxygen high pressure therapy when standard treatments have ...
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ژورنال
عنوان ژورنال: Archives of Medical Science
سال: 2023
ISSN: ['2657-7941']
DOI: https://doi.org/10.5114/aoms/169382